Canine
Hip Dysplasia is a disease effecting primarily
large breeds but occurs in small breed patients as well. The clinical presentation
of CHD is often characterized as bi-phasic with patients having problems
between 6 months and 2 years of age and then again at middle to older age.
Fundamentally, the disease results from a combination of genetic and environmental
factors and requires attention to many issues to prevent, minimize or treat
the disease. The mechanism of genetic transfer is polygenetic which means
many genes are involved in determining the patient's potential for exhibiting
the problems we call Canine Hip Dysplasia. When a patient develops these
problems we say the genetic potential has been phenotypically expressed.
Typically CHD effects both legs, however approximately 10% of patients will
be effected on only one side.
Patient's with CHD often are slow to rise and tire quickly when exercised.
Young patients have gait abnormalities when they run often described
as "bunny hopping". The underlying problem with CHD is the hip components
don't fit together well. This poor fit called "incongruity" results
in abnormal stresses which cause pain, dysfunction and arthritis. Osteoarthritis
secondary to CHD is our biggest enemy in treating the disease. (Insert
normal hips and degenerative hips) Figures
Historically,
veterinarians have focused on treating canine hip dysplasia (CHD) medically
or surgically. As our knowledge base grows, it is becoming more evident
that early intervention is the key to avoiding the high morbidity of
canine hip dysplasia. Total hip arthroplasty (replacement) and excisional
arthroplasty combined with medical management using NSAID's, PSGAGs
(polysulfated glycosaminoglycans) or Slow Acting Disease Modifying Agents
such as glucosamine and chondroitin sulfate will continue as our standard
armamentarium for treating patients with clinical hip dysplasia.
Recent research has shown there are three interventional actions through
which we can significantly impact the developmental component and phenotypic
expression of canine hip dysplasia. These intervention actions are puppy
nutrition (8 weeks-12 months), pubic symphysiodesis (4-5 months) and
triple pelvic osteotomy "TPO"(6 months-12+months). The key to all of
these strategies is veterinarian and owner awareness and implementation
of appropriate screening protocols.
Screening
protocols should be implemented at three points in the puppy's routine
care regime. These screening opportunities are often associated with
wellness examination, ovariohysterectomy or castration. The first screening
exam should occur at approximately 10-12 weeks of age. The patient should
be examined for hip laxity utilizing the Barden test or Ortaloni test
to detect subluxation of the coxofemoral joints. Stress radiographs
should be performed if excessive laxity is identified. The second screening
exam should be performed at 16 weeks. If laxity is present, radiographs
and referral for pubic symphysiodesis should be considered. The third
screening exam is performed at approximately 6 months of age. If laxity
is demonstrated then referral for triple pelvic osteotomy is appropriate.
At each screening examination, continued re-enforcement of nutritional
counseling is vital.
Multiple
studies have shown the single best preventive step veterinarians can
provide to improve the patient's hip phenotype is nutritional counseling.
Each patient should be frequently evaluated to maintain a feeding program
that produces a lean body conformation. The best measures of appropriate
body weight on an every day basis include the ability to easily palpate
the ribs and the presence of tapered waist at the flank fold. This type
of monitoring can be taught to the client but is best performed by the
veterinarian in conjunction with routine wellness examinations and vaccinations.
It is often important to clients that have purchased breeds with high
hip dysplasia incidence that their pets reach maximum body size. Accordingly,
pet owners should know that caloric limitation to produce the desired
rate of growth to prevent phenotypic hip dysplasia does not effect the
total growth of the pet. The key point is that the end result is the
same. It simply takes longer for the patient to achieve its genetic
growth potential.
Pubic
symphysiodesis is a
new procedure designed to produce a more congruent coxofemoral joint
in dysplasia prone individuals which demonstrate hip laxity at an early
age. It must be performed between 31/2 to 41/2 months of age for maximum
effectiveness. It has been shown to be effective in lab animal species
and canines producing statistically significantly greater acetabular
coverage angles in controlled studies. The procedure stimulates premature
closure of the pubic symphysis utilizing electrosurgical techniques.
This alteration results in compensatory lateralization of the acetabulum
and a more congruent hip. Technical errors result in failure of the
growth plate to close, failure of symmetrical closure or uretheral damage.
In patients that would go on to develop congruent hips, the procedure
has not been shown to produce unfavorable side effects.
Triple pelvic osteotomy is a surgical procedure
shown in properly selected patients to produce excellent long term hip
congruity and clinical function. TPO is best performed before any degenerative
changes are present in the joint. This typically means the ideal candidate
is presented between 6 and 10 months of age. Arthroscopic evaluation
of the hip joint is recommended to assess the level of degenerative
change prior to TPO. Many patients are still candidates up to 12 months
and older but require careful assessment. Important selection criteria
include age, hip conformation, degree of degenerative change (arthroscopic
evaluation) and client commitment. In TPO the acetabular segment is
mechanically repositioned to better cover the femoral head.
Total hip arthroplasty is the best alternative
for most adult patients suffering from CHD. We utilize a modular cemented
system at STVS and have excellent results in these patients. Post operative
care, patient size and compliance, and expense are important considerations
in case selection. Excisional arthroplasty is an acceptable alternative
salvage procedure for end stage coxofemoral joint disease or in patients
for whom other treatments are not available.
Excisional arthroplasty, also known as
Femoral Head and Neck Ostectomy (FHO) removes the femur's contribution
to the hip joint. (See Figure 1).
This
allows the top of the femur to be capture by a muscle sling that over
time functions as a false hip joint. Results are variable from case
to case but many patient's have satisfactory outcomes with this procedure.
It requires less post-operative care and is less costly than other surgical
treatments.
In
summary, there are many ways we can intervene to help our patient's
avoid phenotypic expression of canine hip dysplasia or to treat clinically
affected patients. Recent studies have provided excellent evidence so
that we now have the opportunity to intervene earlier and more successfully
than ever before. Veterinarian and owner awareness and early detection
of susceptible individuals can greatly improve our record in beating
this crippling disease that often leaves our patients with the choice
of ineffective medical management or expensive surgical alternatives.
The many options require a complete examination and thoughtful assessment
of the right plan for each patient.