Patent
ductus arteriosus (PDA) is the most common congenital heart defect seen
in dogs. Breeds commonly affected include Poodles, Keeshonds, Cocker spaniels,
German Shepherds, Pekinese, Collies, Shelties, Pomeranians and Welsh corgis.
Females are at an increased risk and a genetic basis is proven in poodles
and suspected in other breeds.
During
fetal development the ductus arteriosus is a normal anatomical structure
that allows fetal blood to bypass the lungs since they are not needed
for oxygenation prior to birth. Normally this vessel, which connects the
pulmonary artery and the aorta, closes nearly immediately after birth
once air expands the lungs. When the vessel remains open or patent, blood
is shunted from the high pressure aorta to the lower pressure of the pulmonary
artery which results in overcirculation of the lungs. The shunting of
blood causes an overload of the left side of the heart, which leads to
dilation and enlargement of the left heart wall. Untreated a PDA will
usually lead to progressive left sided congestive heart failure and pulmonary
edema within the first year of life.
A PDA
will produce a characteristic continuous heart murmur, which is often
noted during physical exam for initial vaccinations. Bounding pulses are
also characteristic of a PDA. Additional diagnostics used to confirm the
presence of a PDA are thoracic radiographs and an echocardiogram or ultrasound
of the heart.
Surgical
correction of a PDA is accomplished by ligation of the ductus to close
the shunt. A left side thoracotomy is performed at the 4th rib space to
isolate the vessel and pass sutures around the PDA. Once the vessel is
ligated the murmur is eliminated and the physiologic abnormalities associated
with the shunt are reversed. A temporary chest tube is used to evacuate
air from the thorax and re-establish negative pressure for the lungs to
expand normally.
After
surgery the animals are treated for pain and the chest tube is usually
removed within 24 hours. Most dogs are discharged 1-2 days after surgery
to recover at home. Prognosis is generally very good especially if corrected
before major secondary changes in the heart have occurred